Comment · Fri, May 1, 2020
🔬 Lab Update: Waters UPLC-MS and Thermo Gas Chromatograph! 🔬
Original post in this thread
MisterYouAreSoDumb · 40 points
Another lab update: Our new Waters UPLC-MS and Thermo GC are finally in! Teams from Waters and Thermo have been on site at our facility installing and doing the IQ/OG on these new awsome machines!
The new UPLC mass spec from Waters is going to allow us a lot more ability and flexibility in method development, method validation, and identification of unknown compounds in various samples. We have a column switcher on this UPLC, so we can have it auto-switch between different columns needed for specific methods. This is crucial when working on an R&D machine that will be doing method development. Sometimes a C18 is just not the ideal column for the analyte. We also have the PDA detector in-line with the QDa mass detector. So we can get a full UV spectrum with peak purity in addition to the mass data. This will allow us to have a much more complete picture of the analyte. Sometimes what you think is a single peak on the UV spectrum is actually multiple things hiding together. The mass detector will show those fragmentation patterns and allow us to break down just what is in a peak at a given retention time. We are going to b…
What they were answering
Kavie_Large · 3 points
This as an analytical chemist... always anoyed hearing you guys in the lab are nothing but overhead and you don't need that instrument we will just send it out to a contract lab only to spend the equivalent amount $ on replicant testing when we cant trust their results. Waters mankes a pretty instument. I ran a static headapace qc from thermo dirict incect on column ma y many moons ago was a robust instrument.
u/MisterYouAreSoDumb
This is why my people in our lab like working for me. I always buy them the toys they need to keep doing cool shit! Some of my guys came over from other supplement companies, and they said they could never get the execs to agree to the equipment they want. Not me! LOL