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Comment · Tue, January 9, 2018 · Ceretropic & Nootropics Depot

Rapid biodegradation of herbal extracts like Bacopa. A power supplement at day one, half as effective after 1 month, placebo after 3 months? Why proper storage is important and how to store it.

Original post in this thread

TheJonManley · 79 points

TL; DR; Yes, herbal extracts might biodegrade relatively quick - unless properly stored. Use common preservation techniques. I elaborate on both below.

There is a lot of awareness about biodegradation of peptides, but not a lot of awareness about biodegradation of dried plant extracts. Biodegradation can take something that is very effective and render it no more valuable than placebo. Thus, it's a very important factor to be mindful of.

I didn't notice any serious discussion about it, so I'll start by by sharing what I've found on one of the herb extracts that I use - Bacopa Monnieri.

I recently read a study concluding that "BM plant material should be used fresh to obtain maximum concentration of active saponins or it should be stored under LS conditions up to 3 months." [1]

Here are numbers from that study:

In the case of the accelerated study the concentration of bacopaside I reduced to 91.20% and the concentration of bacoside A reduced to 68.27% within 1 month from the initial 100% concentration. The samples stored under long-term study showed that the quantity of bacopaside I reduced to 66.99, 45.60, 43.94 and 19.53% in 3, 6, 9 and 12 months respectively,…

What they were answering

weltweite · 1 points

Hi, was wondering if you ever sent an older lot to Alkemist?

Really interested if there was a difference in bacoside levels, as it gets pretty hot where I live in the summer time and I hardly use the air conditioner. Thanks either way!

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

No, thanks for reminding me! We talked about it, but never got a chance to send one off. I'll have my team do that now.

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