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Comment · Thu, January 7, 2016

Supercritical CO2 Saint John Wort extract a.k.a. Hyperforin without hypericin

Original post in this thread

Tablaski · 2 points

I would be very interested if ceretropic would produce preparations including super CO2 Saint John wort extract WITHOUT hypericin

Indeed, this method of extraction allows filtering out hypericin, which was thought for a long time to be the major active compound of SJW, but has since then be retouted to be only a part of its anti depressant effects.

Since there are concerns about the photosensitivity induced by hypericin and doubts about it favorising cataracts (not necessarily backed-up by strong and reliable research though, but I don't know about you but it'd rather take the safest option when it involves the safety of my sight)

I think it is time some company offers the market a product focused on hyperforin and hypericin-free

From what I've seen over the Internet, CO2 supercritical extracts are only sold to businesses or for wholesale, and pure hyperforin from labs is expensive (I don't know if it's because it is synthetised or if removing the other CO2-soluble compounds makes it costly).

Considering SJW is one of the most popular, if not the most self-medicated antidepressant out there, I think it's time to give an option to people to get a strong hyperforin dosage with…

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb

It's not a bad idea, and one that I have thought about for a while. The issue is twofold. One, cost is very high. Perika SJW is very effective, and can be purchased cheaply. I would not be able to compete on price. Two, we would need to have a delivery system that protects the hyperforin from degradation. Perika's system is patented. So we would need to come up with an alternate one, or try to get them to license it. I doubt they would.

That being said, if we can give benefits on top of what Perika does, then bringing out a product that is a bit more expensive could be justifiable. We could make it into a solution to prevent the oxidation, which would not violate the Perika patent. The main hurdle would be the CO2 extraction, and getting good yields. Also, the solubility might be an issue. So we would have to play around with that too.

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