Comment · Sat, January 17, 2015 · Ceretropic
Can the advancements that are being made to Semax be applied to Oxytocin?
Original post in this thread
andrewcb88 · 8 points
Semax -> N-Acetyl Semax -> N-Acetyl Semax Amidate(possibly)
I have no clue about anything peptide wise and it is something that just came to mind.
Oxytocin -> N-Acetyl Oxytocin -> N-Acetyl Oxytocin Amidate
Just curious. Have never tried Oxytocin myself and was never really too interested because of it's lack of ability to cross the BBB and the short half-life. If advancements could be made I would be more interested.
Edit: Or any thoughts on WAY-267,464
What they were answering
FW900 · 6 points
was never really too interested because of it's lack of ability to cross the BBB
Nasal and injected oxytocin are able to cross the BBB. Like most peptides, it has almost no oral bioavailability; the GI track is too harsh of an environment for nearly all peptides.
/u/misteryouaresodumb is there any possibility of Ceretropic offering oxytocin one day?
u/MisterYouAreSoDumb · Ceretropic
Yes, I am using some ideas I got from a study /u/shrillthrill found. It was for smaller mer peptides that have the same, or better, binding to the oxytocin receptor. I was just brainstorming about it yesterday.