Skip to content

Comment · Mon, October 7, 2013

So, we all know too much MDMA in a certain time period is a bad thing. But those who took it daily, when it was legal in the 80's didn't. My question is; How are they doing now? What long term damage occurred?

What they were answering

Toodlum · 2 points

It's not up for debate anymore. We are past the "if" and we are now looking at the "how" and the "extent." There is no perfect or conclusive study and there never will be -- not when something as complicated as the CNS is involved -- but when looking at the bulk of evidence we can draw pretty clear conclusions.

u/MisterYouAreSoDumb

No matter how many times I say it, no matter how many studies I link, no matter how in-depth I get with the mechanisms in vitro and in vivo, in mice, rats primates, and humans, people still say "we don't know."

Other MYASD lines in this thread

Related in the archive

Commentr/DrugsNov 8, 2012

Research Suggests no Neurotoxicity in MDMA

**I'm going to copy what I wrote on another thread:** _____________________________________________________ YES! Keep your damn body temperatures down people! http://www.maps.org/publications/1998_malberg_1.pdf http:

597PiracetamMagnesiumQuercetinDosing
Commentr/DrugsDec 19, 2012

Which substance, in your opinion, is the hardest to remember what happened afterwards? Also, what is your best blackout story?

Ativan (lorazepam) I was going to the Markus Schulz concert one night, here in Phoenix. At dinner, one of my friends rolls a pill across the table to me. He said it was an Ativan. I was like, ohh ok, thanks. I did not i

195
Postr/DrugsNov 22, 2012

MDMA Neurotoxicity Part 1 (Metabolites)

This is probably going to be the first in a series of discussions I start about MDMA. There's just too much information for one post. Therefore, I am going to start with one that is very interesting to me: MDMA's metabol

7776Quercetin
Commentr/DrugsApr 18, 2013

Experts: 5 Signs Your Teen Could Be Using Club Drug 'Molly' - This is one of the dumbest articles I've read in a long time.

>Molly is like the 70s version of crack Wait, what? I think they got their equivocation backwards, and their demographics mixed up. >but because the drug is so highly addicting, he said, "They're buying a lot of it."

72
Commentr/DrugsApr 9, 2013

How fucked am I r/drugs?

Don't ever admit anything to a police officer. EVER! The burden of proof is on them.

52
Commentr/DrugsApr 8, 2013

Man 'took 40,000 ecstasy tablets' - Doctors have revealed details of the biggest recorded user of ecstasy - a man estimated to have taken 40,000 ecstasy pills in his life.

Replying to Mentran · Why no redosing?

The metabolism characteristics of the drug mean that the first dose inhibits the main metabolic pathway, CYP2D6. This means that any subsequent doses are more likely to use the secondary metabolic pathway, CYP3A4. The CY

44Dosing