Comment · Sat, June 15, 2013
MDMA dosage and pre-loading/post-loading for first ever roll?
Original post in this thread
[deleted] · 3 points
I've acquired 5 Red Mortal Kombats from SR, and the vendor describes them as "209 to 226 mg" so I guess I'd call them 200mg. I've also acquired some Alpha Lipoic acid (I'm not positive but I'm pretty sure it's racemic), Vitamin C, Magnesium Citrate, and 5-HTP supplements for pre-loading/post-loading. Here's my plan, as has been advised by rollsafe.org:
* 6 hours before: 250mg Magnesium Citrate
* 1 hour before: Additional 250mg Magnesium Citrate, 2000mg Vitamin C, 200mg Alpha Lipoic Acid
* Roll: Take 3/4 of a pill (I'm a pretty big guy at 6'2" and 220lbs, so I figure a slightly higher dosage would be good)
* 1 hour into roll: Additional 200mg Alpha Lipoic Acid
* 2 hours into roll: Additional 250mg Magnesium Citrate, additional 1000mg Vitamin C
* 3 hours into roll: Additional 200mg Alpha Lipoic Acid, possibly take the final quarter of the pill as a booster depending on how I feel at that point
* 4 hours into roll: Additional 1000mg Vitamin C
* 5 hours into roll: Additional 200mg Alpha Lipoic Acid
* 3 consecutive nights after roll: 100mg 5-HTP before bed
Does this look like a good plan? Am I worrying too much? My main concerns are jaw clenching (had that problem on acid and it hurt…
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb
http://www.reddit.com/r/DrugNerds/comments/15m9sf/mdma_supplementation/
Rollsafe got the info from my post. That goes into much more detail. Also, for some reason he took grapefruit juice off the rollsafe site because some "professor" said it was a risk. That's retarded... The whole point is to prevent the metabolism. Using the fact that it slows metabolism as a deterrent to using it, is the exact opposite of common sense. I'd suggest still using grapefruit juice. It will potentiate your roll and prevent the toxic metabolites.
Your regimen looks good. You might need some Tums to neutralize stomach acids so that the MDMA absorbs faster, though. I would eat 5 hours before your roll, then drop on an empty stomach with Tums. That will help you get higher oral bioavailability.
I'd also suggest taking EGCG with your 5-HTP, to inhibit aromatic L-amino acid decarboxylase in your periphery. This will give your 5-HTP a chance to cross the blood brain barrier before converting to 5-HT.