Comment · Tue, March 19, 2013

Study shows that "MDMA-induced neurotoxicity was dose dependently increased by LSD." Can anyone comment with more information?

What they were answering

KillYourHeroesJesus · 4 points

This is exactly the information I was looking for. Thank you for this and all your posts regarding MDMA neurotoxicity, they are invaluable. Your bit on MDMA metabolites is notably phenomenal. Do you still plan on writing a Part 2?

u/MisterYouAreSoDumb

Yeah, I'll write a part two at some point. I've been doing more nootropics research lately. All the neurological systems are very interdependent, so I jump around a lot when I find interesting info.

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Comment · Mon, March 18, 2013 · 17 pts
What a half-assed study! What were the body temperatures of the groups? This makes sense, though. LSD is a 5-HT2*_a/b/c_* agonist. If you agonize 5-HT2*_c_*, your body temperature is going to rise. Remember all my ranti

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http://www.sciencedirect.com/science/article/pii/0024320584900948 >The results suggest that the elevations in brain 5HT and 5HIAA levels produced by caffeine do NOT enhanced 5HT synthesis, despite significant elevations

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