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Comment · Wed, December 12, 2012

r/drugs Secret Santa

Original post in this thread

Withnail20 · 119 points

OK obviously we could never do this, but I was just thinking how awesome that would be. Just imagine us all sending each other different drugs to try, it would be so exciting!

What they were answering

bwatm · 5 points

Well here's my report on my recent experience. General consensus seemed to be it was pretty pure? Maybe I just took too much? I'm still trying to work it out :/

u/MisterYouAreSoDumb

200mg of pure MDMA will floor you! I've rolled on as little as 75mg of pure crystal from Amsterdam. If you get really pure stuff, it can be strong; even overwhelming at times. Know your source so that you know how to dose it properly. Take 100-125mg of that same stuff, and you will have a much different experience.

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How fucked am I r/drugs?

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Replying to Mentran · Why no redosing?

The metabolism characteristics of the drug mean that the first dose inhibits the main metabolic pathway, CYP2D6. This means that any subsequent doses are more likely to use the secondary metabolic pathway, CYP3A4. The CY

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