Comment · Wed, December 5, 2012
25i-NBOME + Cocaine and MDMA...Anybody have any experience with this combo?
Original post in this thread
BumpSkump420 · 9 points
Or possibly just 25i and cocaine.
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb
MDMA reveres the action of your SERT (serotonin transporters), causing 5-HT to be released. Cocaine also binds to your SERT, effectively stopping the MDMA induced release of 5-HT into your synapse. Taking it during your roll just wastes MDMA.