Comment · Tue, November 6, 2012
Is it easier to lose your shit on shrooms then it is on acid?
Original post in this thread
Frogtech · 26 points
I've seen people say so around here a few times.
And yeah, set and setting are crucial obviously.
What they were answering
thisIsMyDrugAccount · 3 points
I feel like acid is a little more pushy towards the positive end, though. Acid allows you to see the positive aspects of things a little easier than you would sober, so it's easier to be more positive in general.
Mushrooms you're entirely at the whim of whatever is happening around you. If something bad happens, it's a lot harder to think "yeah, but think about the silver lining." Don't get me wrong, I've gotten into that mindset on mushrooms before, but it usually takes a while of highly positive things in the trip to get me to the point where nothing can bring me down. I feel like acid you start off with that mindset.
u/MisterYouAreSoDumb
LSD is a partial dopamine receptor agonist. This makes it more pushy toward feeling good. However, since the trip lasts a long time, toward the latter part of the experience your dopamine receptors start to down-regulate. This could be a reason that some people have it start to turn south toward the latter half. That is merely my postulation though. 4-oh-dmt is not a dopamine receptor agonist, so it will not push your risk reward system on it's own. It's up to your brain to release it if it wants to.