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Comment · Fri, November 2, 2012

How do I know if I have MDMA induced depression?

Original post in this thread

Bazing365 · 11 points

Ok so starting around June this year I discovered the incredible MDMA experience. After taking it my first time, I took it roughly every 3 or 4 weeks with the occasional 2 week wait. I know that doing it in this frequency is ill advised but I was under the impression that I could somehow handle it. Fast forward to the last time I rolled (2 weeks ago) and the crash afterwords was absolute HELL. I was completely drained of energy, felt physically ill (nausea and soreness), and felt completely depressed.

Now, I have had a history of dysthymia, but the feeling I had after this crash was in a complete other league. My cognitive process was completely negative and I couldn't stop thinking about suicide and how shitty everything was. Fast forward to now (2 weeks later) and I still feel extremely weak (albeit able to make it to the 2 classes I have a week now) and the negative cognition hasn't abated even minutely. Usually after a roll i experience maybe one day or two of tiredness and a lowered mood but nothing even remotely close to this reaction.

To get to the point, Do you fellow redditors think this is solely the effects of MDMA abuse, or a combination of the MDMA crash with preexi…

What they were answering

_angel · 1 points

Regardless if neurotoxicity has been proven, life long depression is a real thing, and the number 1 thing that causes it is bumping, or at least for everyone I've bumped into with problems in the long run. Please be safe.

u/MisterYouAreSoDumb

Bumping? Do you mean increasing dosage? If so, I did tell him that I was not encouraging upping his dosage, and encouraging lots of time off. However, my key point was body temperature. MDMA will not cause neurotoxicity if you keep your body temperature regulated. Neurotoxicity is the real danger here. Obviously receptor down-regulation comes into play when we are talking about depression, but that is reversible. Destroying your axon terminals, because you did not know to keep your body temp down, creates permanent damage.

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