Comment · Sat, November 30, 2024 · ND Owner
Xylaria Nigripes Fungus: Product Request
Original post in this thread
Dannanelli · 9 points
I stumbled upon an ingredient named Zylaria which is a patented form of Xylaria Nigripes Fungus (aka Wu Ling Shen) which is a mushroom that grows in termites nests.
It looks like it has potential to calm the CNS, and help with relaxation, sleep, and depression:
“Recent studies show that XN have a tranquilizing effect on the central nervous system, it could modulate some physiological functions such as anti-oxidative damage [2-4], anti-inflammatory activity [5] and protecting carbon tetrachloride-induced liver injury in mice [6]. XN is also used to relieving depression and treating trauma [7,8]. In traditional Chinese medicine (TCM), XN is commonly used to regulating wake and sleep. Previous studies have shown that XN could induce sleepiness and maintained sleep time in insomnia patients [9,10].
Previous study shows that Xylaria nigripes could promote sleep and decrease autonomic locomotion, and Xylaria nigripes exert its sedative and sleep-promoting effect through activating the receptors of GABA [20]. Furthermore, study has demonstrated that GABA-mediated excitation regulates CREB activation [34], and GABA-B receptor activity upon ethanol exposure could modulate the expressio…
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u/MisterYouAreSoDumb · ND Owner
I've had a sample on my desk for a bit. I have not tried it yet. I will get around to it soon. Been beta testing a lot of other stuff recently. It's on our radar, though.