Comment · Fri, September 23, 2022 · ND Owner
Berberine
Original post in this thread
schowdur123 · 18 points
Anyone use and have good results using Berberine as a nootropic? Thank you.
What they were answering
jimmythegreek1 · 2 points
Yeah that's why I'm confused. Good share I am going to dig into this paper. I'm sure I will be confused maybe u/MisterYouAreSoDumb can help :p
u/MisterYouAreSoDumb · ND Owner
Yeah, it is generally a good thing.
https://www.sciencedirect.com/science/article/pii/S0753332219314970
Intervention with metformin or berberine modified the gut microbiome in db/db mice, increasing the number of SCFA-producing bacteria (e.g., Butyricimonas, Coprococcus, Ruminococcus) and reducing opportunistic pathogens (e.g., Prevotella, Proteus). An increased abundance of other probiotics including Lactobacillus and Akkermansia was also observed. Berberine and metformin can modulate the composition of the gut microbiome and reduce body weight, blood glucose levels, and intestinal inflammation in db/db mice, which demonstrates their effectiveness in the reduction of diabetic complications in this model.