Comment · Mon, November 29, 2021 · ND Owner
Does ND test for N-Nitrosodimethylamine pollution in it's products?
Original post in this thread
Ovulating_Oyster · 8 points
I've read about quite a few recalls from Metformin, Valsartan, and even Zantac pulling products due to finding even trace amounts of this in their inventory. Does ND or other vendors do similar diagnostics on their products?
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · ND Owner
No, nobody does. There is no reason to. Those other drugs were pulled from the market because they have dimethylamine groups in them, and they found that too high of levels of N-nitrosodimethylamine could either be formed in the synthesis process, or form in the body after ingestion. All of them have N-nitrosodimethylamine groups except for Valsartan, which has a dimethyl group not attached to a nitrogen. That had an issue because the Chinese manufacturer changed the synthesis to use dimethylformide and sodium nitrate to improve yields, which led to the creation of N-nitrosodimethylamine during the synth. If you don't have a N-nitrosodimethylamine group in the molecule, or don't have a dimethyl group with a nitrogen source in the synthesis, it's not possible to have created.