Comment · Sun, February 7, 2021 · ND Owner
Replicating LSD microdose
Original post in this thread
autoi999 · 33 points
I like LSD microdosing since it
* Increases verbal fluency
* Processing power / capacity
* Calms the mind for clear thinking
* More "spiritual"
What I don't like is the non-replicability of effects (once every 3 days) and that it's illegal and often the wrong dose.
What nootropics from ND could possibility replace the microcode?
What they were answering
BrdigeTrlol · 2 points
u/MisterYouAreSoDumb · ND Owner
A monoclonal antibody directed against the human growth differentiation factor 15 (GDF15; MIC-1), with potential anti-cachexia activity. Upon administration, ponsegromab targets and binds to GDF15, thereby preventing the binding of GDF15 to its receptor glial-cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL) and blocking GDF15/GFRAL-mediated signaling. This may abrogate loss of appetite and uncontrolled weight loss associated with high serum levels of GDF15. GDF15, a stress response cytokine and divergent member of the transforming growth factor beta (TGF-beta) superfamily, plays a key role in the regulation of body weight through central mechanisms. High GDF15 plasma levels, as seen in individuals with advanced cancers, are associated with loss of body mass.
Wow, that's pretty cool!