Comment · Sun, April 19, 2020
Any chance of offering kappa antagonist in your store?
Original post in this thread
Azetinho · 8 points
Hello!
It’s a pity that there’s no easy way to obtain a potent kappa-opioid antagonist on the market. There are a bunch of compounds such as Norbinaltorphimine, JDTic or CERC-501 but none of them can be bought in traditional way. I know that there are probably some obstacles but Nor-BNI seems like a good candidate to offer. There’s such a big potential in these noots for uplifting mood, reducing anhedonia and dissociation.
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb
There is certainly potential there. However, the FDA and banks are sketched out by anything that binds to the opioid receptors. Sure, we understand the difference between a μ-opioid agonist and a κ-opioid antagonist, but most people don't. So they group it all together. It would be a hard sell to convince our bank to allow us to sell a synthetic compound with opioid affinities.